Polynucleotides are a next-generation injectable bio-stimulator designed to support skin regeneration and repair at a cellular level. Rather than adding volume, this treatment works by stimulating your skin’s natural processes, improving elasticity, firmness and overall skin quality.
At our Dublin clinic, Polynucleotides are used as part of a personalised medical approach to skin rejuvenation, helping to restore a healthier, more youthful complexion with natural-looking results.
Polynucleotides are naturally derived injectable compounds that stimulate tissue regeneration by activating fibroblast cells. This process encourages the production of collagen and elastin, key components responsible for skin strength, elasticity and resilience.
They are particularly effective in improving skin quality in delicate areas where traditional injectables may not be suitable.
Polynucleotides boost collagen and elastin by up regulating the fibroblast cells, as well as improving tissue regeneration and restoring skin tone and elasticity.
It has an antioxidant and hydrating effect in addition to the bio-remodelling, therefore resulting in skin that looks and feels healthier.
Philart Polynucleotides are a cutting-edge treatment option for those of us seeking natural-looking, rejuvenated skin.
Based on natural ingredients The Polynucleotides (PN) are of natural origin and derived from European freshwater fish intended for human consumption, with full control over the production chain.
PhilArt treatment involves a sequence of pin prick injections into the facial areas normally over 2-3 sessions about 2-3 weeks apart.
It only takes about 15 minutes and you can resume your normal daily activities afterwards.
For patients who are looking to address fine lines, wrinkles & loss of elasticity on the face & neck area.
It treats various concerns and is an excellent option for under-eye crepiness, puffiness, wrinkles, and hollows..
Results from Polynucleotides develop gradually as skin regeneration takes place. Improvements in skin texture and quality are typically seen over the weeks following treatment, with results lasting several months depending on individual skin condition and treatment plan.
PhilArt is a new Polynucleotide injectable treatment that helps boost Collagen synthesis and it more adept at skin tone and texture for more delicate areas such as the eyes and neck.
Profhilo is more of a skin hydrator and booster helping giving the skin more firmer looks with out the effects of volumisation that dermal HA fillers are known for.
While both treatments focus on improving skin quality, they work in different ways. Polynucleotides are primarily regenerative, stimulating cellular repair and collagen production, making them ideal for delicate or compromised skin.
Profhilo, on the other hand, focuses more on deep hydration and skin remodelling. A consultation will help determine which treatment, or combination, is most suitable for your skin.
We administer Polynucleotides through minimally invasive micro injections. So pain is minimal .
Polynucleotides
1 Session (eyes) – 325
Course of 3 – 900
We’re incredibly proud of the feedback we get. We’d encourage you to read all of our many 5 star TrustPilot reviews from happy customers who love their results.
Nicole Joyce
As always, Dr Dallas was nothing but professional! I had lip augmentation and Anti-Wrinkle with Dallas and he done an excellent job. My mother also had Anti-Wrinkle and Profhilo.

We are both so happy with the results. We wouldn’t trust anyone else with out treatments and would highly recommend Dallas for any treatment anyone is considering. We will most definitely be returning.
Sharon
I would 100% recommend Dr Dallas, his manner and procedure/product knowledge is magnificent, I felt reassured the first time I met him enough to go back and let him do what I wanted to have done, and more! Absolutely love my new skincare routine which he also advised me on. Words cannot depict how happy I am since Dr Dallas carried out my treatments.
Natalie
Dr D is a true king! The ultimate professional and a true gentleman. I moved abroad last year but still fly home just to see Dr Dallas and will never trust anyone else with my face. I’m not sure which I look forward to the most - my post treatment glow up or his wonderful chats! Offering Hydrafacials in the clinics now is also a great extra benefit.
Medical Expertise You Can Trust
Polynucleotides hydrate, regenerate and stimulate fibroblasts and Collagen production. Skin boosters don’t stimulate regeneration of skin even though they hydrate skin.
Fine lines, scars, wrinkles, rosacea & overall skin quality.
It can take 4 weeks to see initial results & the most noticeable results will be visible approx 2 months after 2nd treatment
Depending on age & skin concerns, results can last from 6-12 months.
Combining treatments can enhance overall skin rejuvenation and Polynucleotides compliment nearly all aesthetic treatments.
All Polynucleotides treatments are carried out following a detailed aesthetic consultation to ensure safety, suitability and optimal results. Treatments are tailored to your skin condition, concerns and long-term aesthetic goals.
Find out if Polynucleotides are right for your skin. Book a personalised consultation with our medical aesthetics team in Dublin.
If you have further questions or would like personalised advice, our team is here to help. A consultation allows us to assess your concerns, explain your options clearly and determine whether anti-wrinkle injections are right for you.
At Dr Dallas Clinic, we want to make sure you can access the best treatments without worrying about the upfront cost. With Humm, you can break the cost into more manageable payments and spread them out at your convenience.
At Dr Dallas Clinic, we want to make sure you can access the best treatments without worrying about the upfront cost. That’s why we offer the option to finance the most expensive treatments and personalised treatment plans with Humm. With Humm, you can split the cost into more manageable payments and spread them out at your convenience.